Clinical-Grade and Advanced Technologies in Stem Cells and Extracellular Vesicles — From Bench to Bedside
We are pleased to announce the launch of the Stem Cells and Extracellular Vesicles Educational Day, a distinguished scientific event held under the patronage of Mansoura University, Faculty of Pharmacy, and the Professional Master of Immunology and Regenerative Medicine. Organized by Elbeltagy Therapeutics, a biotech company that created the first dental pulp stem cell biobank Prototype in Egypt, and delivered in collaboration with the Healthcare Professionals Network for Egypt (HPNE), this special day brings together leading experts, pioneering researchers, and major industrial partners in the field. The event proudly hosts keynote speakers with extensive experience in stem cell science and extracellular vesicle technologies, offering attendees a rich and insightful educational experience.
Core Topics
- Clinical Stem Cell Platforms
- How therapeutic stem cells are collected, expanded, characterized, cryopreserved, and banked.
- Ethical and regulatory requirements, including donor consent, pediatric donors, eligibility criteria, and long-term traceability.
- Quality control and release specifications for a cell product intended for clinical use.
- Latest advances in stem cell applications in preclinical models and near-clinic programs.
- GMP-grade manufacturing of stem cells, including:
- 3D bioreactor expansion
- Microcarrier-based culture systems
- Chemically defined / xeno-free media
- Extracellular Vesicles (EVs)
- Scalable EV production using controlled, closed processes:
- Ultrafiltration
- Tangential flow filtration (TFF)
- Size-exclusion chromatography (SEC)
- EV batch testing and release criteria: identity, purity, sterility, potency.
- Single-EV characterization technologies and EVs from body fluids as diagnostic tools.
- EV formulation and use in:
- Therapeutic applications (immune modulation, wound repair, chronic and acute disease targets)
- Precision delivery and targeted therapy through EV engineering
- Clinical-grade EV development: opportunities and current challenges
- Plant-derived EVs for cosmetic and skin applications (regeneration, anti-scarring, repair)
- Industry perspective: learn from industry leaders specializing in GMP-grade stem cell production, EV isolation, EV characterization, and EV diagnostics to guide participants on how to build translational pipelines.
Why Attend?
See how stem cells and EVs move from lab work to real, regulated products. Learn how cells and EVs are manufactured, tested, qualified for use, and prepared for clinical and cosmetic applications. Understand what “bench to bedside” truly requires in terms of GMP, documentation, and quality. Meet experts from both academia and industry. After the event, you can submit your own technical questions and get guidance from our network.
Who Should Attend?
Researchers in regenerative medicine and molecular biology, clinicians (including dentists and oral surgeons), biobank and QC leads, graduate students and early-career scientists, startup founders in advanced therapeutics, cosmetic/skin innovation teams, and anyone in Egypt or the MENA region aiming to build a regulated stem cell or EV-based product pipeline.
This day represents a strategic collaboration between Elbeltagy Therapeutics and HPNE to establish a serious, quality-driven pathway for stem cell banking and EV-based therapeutics in the region.
Keynote Speakers and Industry Partners
Prof. Bernd Giebel
Prof. Bernd Giebel – Founder of the German Society for Extracellular Vesicles (GSEV).
Leads the Extracellular Vesicles research group at the Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen (UDE)
Learn more
https://transfusionsmedizin.uk-essen.de/giebel-lab/
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Prof. Dr. Holm Zähres
Prof. Dr. Holm Zähres is a stem cell scientist at Ruhr University Bochum (Institute of Anatomy, Department of Anatomy and Molecular Embryology). He works on pluripotent stem cell engineering, iPS-cell reprogramming, and genome-editing-enabled disease modeling, and contributes to the international Master of Science in Stem Cell Medicine program. He is affiliated with the Stem Cell Network NRW.
Learn more
- RUB Anatomy / Stem Cell Engineering profile: https://www.anatomie.ruhr-uni-bochum.de/en/zaehres/
- MSc Stem Cell Medicine program: https://international-academy.rub.de/program/stem-cell-medicine/
- Stem Cell Network NRW – Stem Cell Engineering group: https://www.stammzellen.nrw.de/en/research/research-groups/stem-cell-engineering
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Prof. Dr. Basant Kumar Thakur
PD Dr. Basant Kumar Thakur leads the Cancer Exosome Research Lab at University Hospital Essen (UDE), working on extracellular vesicles and EV-associated DNA as functional mediators and biomarkers in cancer.
Learn more
- ZMB profile: https://www.uni-due.de/zmb/members/basant-kumar-thakur.php
- Group page: https://kinderklinik3.uk-essen.de (Cancer Exosome Research Lab)
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Dr. Ayman Refaie
Chief of the Nephrology & Transplantation Unit and Vice Director of the Urology & Nephrology Center, Mansoura University.
Dr. Refaie is a leading clinician-scientist and a key member of Prof. Dr. Mohamed Ghoneim’s team, working on innovative stem cell–based approaches for the treatment of diabetes mellitus and its complications. Over the past 15 years, their group has contributed pioneering clinical and translational work, helping to bridge the gap between experimental stem cell therapies and real-world patient care.
Learn more
https://scholar.google.com/citations?user=i3kPwV4AAAAJ&hl=en
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Prof. Khalid B. Selim
Vice Dean for Graduate Studies & Scientific Research
Faculty of Pharmacy, Mansoura University
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Dr. Mirhan N. Makled
Associate Professor of Pharmacology and Toxicology
Director of the Professional Master of immunology and regenerative medicine
Faculty of Pharmacy, Mansoura University
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EXDOUS Biosystems
The global leader in GMP-compliant EV isolation technologies, which represents a real step toward translating EV research from the lab to clinical and industrial applications.
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TAmiRNA
TAmiRNA is a biotech leader in microRNA biomarker discovery, using comprehensive RNA profiling from extracellular vesicles (EVs) to develop validated diagnostic signatures. They focus on advancing precision medicine for age-related diseases such as osteoporosis and cardiovascular conditions.
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BioThrust
BioThrust is a Germany-based SME company revolutionizing cell therapy manufacturing with the ComfyCell™️ bioreactor, featuring the unique Membrane Stirrer technology. This platform delivers unparalleled gas transfer and minimal shear stress through bubble-free aeration, enabling the scalable, gentle cultivation of sensitive cells (like MSCs, iPSCs) and robust production of extracellular vesicles (EVs).
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Sartorius
Sartorius is a global leader in bioprocessing and laboratory technologies, offering advanced solutions for scalable extracellular vesicle (EV) manufacturing. With deep expertise spanning process development to pilot-scale production, Sartorius supports researchers and industry partners in optimizing EV workflows for efficient, high-quality manufacturing.
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Beckman Coulter
Beckman Coulter Life Sciences is a global leader in flow cytometry, particle analysis, and automated laboratory solutions. The company’s innovations, including the CytoFLEX and CytoFLEX Nano platforms, enable high-sensitivity detection and advanced characterization of extracellular vesicles, cells, and nanoparticles. Beckman Coulter supports researchers worldwide in accelerating discoveries across immunology, oncology, regenerative medicine, and translational science.
https://www.beckmancoulter.com/
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Cytek Biosciences
Cytek Biosciences is a global pioneer in spectral flow cytometry and imaging-based cellular analysis, delivering high-parameter systems that enable deep immune profiling and nanoscale extracellular vesicle research. With platforms like the Aurora™, Northern Lights™, and Amnis® ImageStream®, Cytek empowers scientists to achieve higher resolution, sensitivity, and throughput in both basic and translational research.
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Particle Metrix GmbH
Particle Metrix GmbH is a German company specializing in high-sensitivity nanoparticle characterization with a strong focus on Nanoparticle Tracking Analysis (NTA). The company develops and manufactures the ZetaView®️ platform, which enables simultaneous measurement of particle size, concentration, and zeta potential in liquid samples. Their instruments are widely used for the analysis of extracellular vesicles, exosomes, viruses, liposomes, and other nanoscale particles in biomedical and nanotechnology research. Particle Metrix combines hardware innovation with advanced software to deliver robust, user-friendly workflows suitable for both routine measurements and complex R&D applications. By offering optimized reagents, application support, and training, they help laboratories implement reliable, reproducible nanoparticle characterization. Through continuous development and close collaboration with the EV and nanoparticle research community, Particle Metrix contributes to advancing quality standards in nanoscale analytics.
https://www.particle-metrix.com
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Elbeltagy Therapeutics
Elbeltagy Therapeutics is a biotechnology startup based in Mansoura, Egypt, dedicated to advancing regenerative medicine through dental-derived mesenchymal stem cells and engineered extracellular vesicles (EVs), with a clear focus on clinical translation. The company is co-leading Egypt’s first Dental Pulp Stem Cell (DPSC) Biobank initiative and is developing scalable -ready platforms for stem cell and EV-based therapeutics.
https://elbeltagytherapeutics.com/
Participation / Registration
- Date & Time: December 15th, 2025. 9:40-15:45 EET (Cairo time).
- Registration link:
https://forms.gle/cUHrexoL1M31HPAA9 - Registration is mandatory and must be completed before the announced deadline.
- The event will be delivered live online, with real-time interaction.
- Participation is free of charge.
For full details, download the event brochure.
For more information:
Phone: +20 102 704 0566
Email: Info@elbeltagytherapeutics.com, info@hpnegypt.com
Facebook: https://www.facebook.com/elbeltagytherapeutics
X (Twitter): https://x.com/elbeltagyco
LinkedIn: https://www.linkedin.com/in/elbeltagytherapeutics/
Instagram: https://www.instagram.com/elbeltagytherapeutics/
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